胰岛素样生长因子-1与糖尿病慢性并发症
Insulin-like growth factor-1 and diabetic chronic complications
胰岛素生长因子-1(IGF-1)是一种结构与功能都与胰岛素类似的蛋白多肽.IGF-1广泛存在于机体各组织中,参与机体多种生理、病理过程.IGF-l通过多条途径影响糖尿病心、脑、肾、神经等慢性并发症的发生、发展.研究其作用机制将为糖尿病慢性并发症的治疗提供新的思路.
更多Insulin-like growth factor-1 (IGF-1) is a kind of protein polypeptide which widely exists in the body tissue and its structure and functions are similar to insulin.IGF-1 involves in many pathological and physiological process.Through a variety of ways,IGF-1 affects the occurrence and development of heart,brain,kidney,nerves and other chronic complications of diabetes.Exploring the mechanism of IGF-1 provides new ideas for the treatment of diabetic chronic complications.
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