广西省南宁地区一常规体检人群高尿酸血症患病率调查及与血脂相关性的研究
The prevalence of hyperuricemia and its relationship to blood lipids in a population for routine check-up in Nanning, Guangxi province
本研究纳入4602名南宁地区常规体检者,检测分析尿酸、总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇.结果显示体检人群高尿酸血症总患病率为19.8%,其中男性为28.8%,女性为9.4%;高尿酸血症组中尿酸与血脂水平高于尿酸正常组(均P<0.01);尿酸与总胆固醇、甘油三酯、低密度脂蛋白胆固醇呈正相关,与高密度脂蛋白胆固醇呈负相关;体检人群高总胆固醇血症患病率为30.8%,高甘油三酯血症为22.2%;Logistic多因素回归分析得出男性、高总胆固醇、高甘油三酯、高低密度脂蛋白胆固醇可能为高尿酸血症的危险因素;高密度脂蛋白胆固醇为保护因素.结果提示广西南宁地区高尿酸血症患病率较高,高尿酸水平与血脂异常密切相关.早期加强对高尿酸血症的干预,能有效减少相关疾病的发生.
更多In 4 602 subjects for routine check-up,blood uric acid,total cholesterol,triglyceride,high density lipoprotein-cholesterol,and low density lipoprotein-cholesterol were determined.Results showed that the overall prevalence of hyperuricemia in Nanning,Guangxi was 19.8% (28.8% in male,9.4% in female).Blood uric acid and lipids in hyperuricemia group were higher than those in normal uric acid group(all P<0.01).Serum uric acid had a positive correlation with total cholesterol,triglyceride,low density lipoprotein-cholesterol,but it was negatively correlated with serum high density lipoprotein-cholesterol.The prevalence of hypercholesterolemia was 30.8%,and that of hypertriglyceridemia was 22.2%.Logistic multi-factor regression analysis showed that men,high total cholesterol,triglyceride,and low density lipoprotein-cholesterol could be independent risk factors for hyperuricemia,and that high density lipoprotein-cholesterol was a protective factor.The prevalence of hyperuricemia in population of Nanning,Guangxi during health examination is high.Hyperuricemia is closely associated with dyslipidemia.Timely intervention of hyperuricemia can reduce the related diseases effectively.
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