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Glifeet 检查餐在结肠镜肠道准备中的应用初探

Evaluation of Glifeet in bowel preparation before colonoscopy

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目的:初探 Glifeet 检查餐应用于结肠镜肠道准备中的安全性及有效性。方法采用单盲、随机、对照试验方法,将67例准备接受结肠镜检查的住院患者分为2组,于结肠镜检查前1 d 分别常规进食少渣半流食(常规饮食组,31例)或 Glifeet 检查餐(检查餐组,36例)。患者于结肠镜检查前1 d 晚7点口服复方聚乙二醇电解质散1000 ml,并于检查当日8点口服上述清肠液2000 ml。观察2组患者肠道清洁度及不良反应。结果检查餐组患者服用清肠液后第1次排便时间[(77.43±54.21)min]较常规饮食组[(149.35±118.15)min]明显缩短(P =0.002)。检查餐组排便次数[(11.44±6.95)次]多于常规饮食组[(8.74±3.58)次],但2组差异无统计学意义(P =0.055)。2组患者均未发生严重不良反应。检查餐组波士顿肠道准备评分标准(BBPS)总分略优于常规饮食组(P =0.822)。检查餐组右侧结肠清洁度评分[(2.56±0.50)分]明显优于常规饮食组[(2.23±0.81)分](P =0.045)。结论结肠镜检查前1 d 使用 Glifeet 检查餐可安全、部分有效地改善肠道准备效果,并满足多数患者肠道准备期间身体所需的基本热量。

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abstracts:

Objective To investigate the safety and effectiveness of Glifeet in bowel preparation before colonoscopy.Methods A prospective,single blind,randomized controlled trial of patients undergoing colonos-copy was conducted.A total of 67 inpatients were randomized to the control group,who received a low-residue and semiliquid diet (n =31)and the experimental group,who received Glifeet all day (n =36)before the proce-dure.All patients took polyethylene glycol electrolyte powder 1 000 ml at 7 pm on the day before colonoscopy and 2 000 ml at 8 am on the examination day.Bowel preparation quality was scored using the Boston Bowel Prepara-tion Scale (BBPS).Side effects were also observed.Results The time of the first bowel movement of the experi-mental group was significantly shorter [(77.43 ±54.21)min VS (149.35 ±118.15)min,P =0.002].An in-creased defecating frequency was observed in the experimental group,but there was no significant difference when compared with the control group (11.44 ±6.95 VS 8.74 ±3.58,P =0.055).Patient tolerance and acceptance did not differ.There was no significant difference in BBPS between the two groups.But the bowel preparation quality of the right colon was significantly better in the experimental group (2.56 ±0.50 VS 2.23 ±0.81,P =0.045). Conclusion Glifeet could meet the needs of basic energy in most patients for colonoscopy.Furthermore,Glifeet is well tolerated and can partially improve the quality of bowel preparation.

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